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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND4A
All Species:
9.09
Human Site:
S1217
Identified Species:
28.57
UniProt:
Q7Z401
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z401
NP_001138295.1
1863
209244
S1217
M
Y
M
N
N
M
S
S
P
L
T
S
R
T
P
Chimpanzee
Pan troglodytes
XP_001174614
1863
209302
S1217
M
Y
M
N
N
M
S
S
P
L
T
S
R
T
P
Rhesus Macaque
Macaca mulatta
XP_001110040
1863
209085
S1217
M
Y
M
N
N
M
S
S
P
L
T
S
R
T
P
Dog
Lupus familis
XP_852698
1865
208924
P1219
Y
M
N
N
M
S
S
P
L
T
S
R
T
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1Y4
1499
164722
K876
G
G
R
L
R
W
A
K
L
R
N
V
V
L
G
Rat
Rattus norvegicus
XP_342288
1485
163205
K862
N
K
A
V
L
E
S
K
W
P
S
G
T
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413911
1870
209117
L1220
M
N
N
M
S
S
P
L
S
S
R
A
P
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919990
1942
214159
I1292
Q
G
S
N
P
E
S
I
N
C
P
D
S
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.5
94.4
N.A.
41.3
41
N.A.
N.A.
80.4
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.1
97
N.A.
55.5
55.2
N.A.
N.A.
88.4
N.A.
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
0
6.6
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
6.6
13.3
N.A.
N.A.
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
13
0
0
0
0
13
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
25
0
0
0
0
0
0
0
0
0
13
0
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
13
% I
% Lys:
0
13
0
0
0
0
0
25
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
13
13
0
0
13
25
38
0
0
0
13
0
% L
% Met:
50
13
38
13
13
38
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
13
25
63
38
0
0
0
13
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
13
0
13
13
38
13
13
0
13
38
38
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
13
0
0
0
0
13
13
13
38
0
0
% R
% Ser:
0
0
13
0
13
25
75
38
13
13
25
38
13
13
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
13
38
0
25
38
0
% T
% Val:
0
0
0
13
0
0
0
0
0
0
0
13
13
0
0
% V
% Trp:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% W
% Tyr:
13
38
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _